Transillumination of renal biopsy specimens for rapid identification of glomeruli

PCR and RFLP Analysis for Identification and Typing of Helicobacter pylori Strains from Gastric Biopsy Specimens

Rapid processing of renal glomeruli for electron microscopy.

Recently we reported a new fine-needle aspiration biopsy method to obtain single glomeruli for electron microscopy in diagnostic and investigative pathology of the kidney. The small size and fragmentary nature of the specimen obtained by this technique necessitated a special device for collecting and processing the tissue for electron microscopy (Pasternack et al., 1978). A new and simpler devi...

Best Practice No 160 Renal biopsy specimens

Taking a kidney biopsy is not a trivial procedure. The sample is almost invariably smaller than the pathologist would like. Investigation usually requires division into even smaller samples to permit the application of specialist techniques. In some cases the biopsy is taken not for diagnosis, but to assess the extent of tissue damage. The clinical need is sometimes extremely urgent. These feat...

Percutaneous renal biopsy specimens in stone formers.

A series of renal biopsy specimens taken at the time of percutaneous nephrolithotomy were investigated for the presence and location of foci of microcalcification. Calcium was found in 18 of 25 (72%) of biopsy specimens from stone formers and in only seven of 30 (23%) of control biopsy specimens. This may indicate defective intrarenal handling of calcium as plasma calcium concentration was norm...

Autophagy by podocytes in renal biopsy specimens.

Autophagy, a process of bulk protein degradation and organelle turnover, is induced under starvation conditions in yeast and plays an important role in developmental processes and human diseases. Autophagy is a nonapoptotic form of programmed cell death. Disturbances in autophagy and programmed cell death may lead to cancer and several degenerative diseases in humans. During the routine ultrast...